New York (CNN) -- Four people thought to be connected to the drugs found in late actor Philip Seymour Hoffman's apartment were arrested late Tuesday night, law enforcement officials told CNN.
During the raid that yielded the arrest of the three men and one woman, police recovered 350 glassine-type bags of what is believed to be heroin, the officials said.
No additional information was released.
When police were called to Hoffman's fourth-floor Manhattan apartment Sunday, they found the actor lying on the bathroom floor with a syringe in his left arm. He was wearing shorts and a T-shirt, his eyeglasses still resting on his head, according to law enforcement sources familiar with the inquiry.
Investigators discovered close to 50 envelopes of what they believed was heroin in the apartment, the law enforcement sources said. They also found used syringes, prescription drugs and empty glassine-type bags, the sources said.
Hoffman's final hours
No fentanyl found
Preliminary tests Tuesday showed the heroin recovered from the apartment does not contain fentanyl, a law enforcement official told CNN. More testing will be done.
Fentanyl is a powerful narcotic used to treat cancer patients' pain.
Last week, Maryland officials said heroin tainted with fentanyl had claimed at least 37 lives since September. And last month, at least 22 people died after using heroin mixed with fentanyl in western Pennsylvania.
While results of an autopsy will definitively reveal exactly how Hoffman, 46, died, the role heroin may or may not have played is a key part of the investigation.
Final hours
Police are trying to piece together the actor's movements last weekend as they look for anyone who might be linked to the drugs that apparently killed him.
On Tuesday, a law enforcement source told CNN that the night before Hoffman died, he withdrew $1,200 from a grocery store ATM near his apartment.
Hoffman got the money in six transactions Saturday night, according to the source.
A witness told investigators he saw the Oscar-winning actor talking to two men wearing messengers bags about 8 p.m.
Police are also reviewing surveillance video, including one of a restaurant where Hoffman had brunch Saturday morning with two people.
How heroin kills you
'I'm a heroin addict'
In a 2011 interview with "60 Minutes," Hoffman discussed his past struggles with drug and alcohol addiction.
"Anything I could get my hands on, I liked it all," he said.
Fear, Hoffman said, made him sober up.
"You get panicked. ... I was 22 and I got panicked for my life, it really was, it was just that," he said. "And I always think, 'God, I have so much empathy for these young actors that are 19 and all of a sudden are beautiful and famous and rich.' I'm like, 'Oh my God. I'd be dead.'"
But last year, Hoffman said he'd fallen off the wagon, started taking prescription pills and slipped into snorting heroin, according to TMZ.
Magazine writer John Arundel said he met the actor at the Sundance Film festival in Utah two weeks before his death.
"I said, 'What do you do? And at that point, he took off his hat and he said, 'I'm a heroin addict,' " Arundel said.
"Didn't look like he was (joking). Seemed like he was having one of those 'coming to God' moments- where it just stuck him as, 'this is the revelatory moment.'"
But actor George Clooney said he had dinner with him a few months ago, and he seemed fine.
"I have to say he seemed in pretty good shape," Clooney said. "I mean, there's no way to explain it."
Dim the lights
Family and close friends of the actor will hold a private funeral service in New York. Plans are also under way for a memorial service later this month. No information on the dates was available.
On Wednesday night, the famed Broadway theater district will dim its marquees for one minute at 7:45 p.m. in Hoffman's memory.
Hoffman appeared on Broadway three times.
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